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Tatsuzo Mizukami Selected Research

amatuximab

10/2021Early administration of amatuximab, a chimeric high-affinity anti-mesothelin monoclonal antibody, suppresses liver metastasis of mesothelin-expressing pancreatic cancer cells and enhances gemcitabine sensitivity in a xenograft mouse model.
2/2021Mesothelin blockage by Amatuximab suppresses cell invasiveness, enhances gemcitabine sensitivity and regulates cancer cell stemness in mesothelin-positive pancreatic cancer cells.
9/2018The anti-mesothelin monoclonal antibody amatuximab enhances the anti-tumor effect of gemcitabine against mesothelin-high expressing pancreatic cancer cells in a peritoneal metastasis mouse model.

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Tatsuzo Mizukami Research Topics

Disease

8Neoplasms (Cancer)
10/2021 - 09/2014
5Pancreatic Neoplasms (Pancreatic Cancer)
10/2021 - 09/2014
3Neoplasm Metastasis (Metastasis)
10/2021 - 05/2011
2Stomach Neoplasms (Stomach Cancer)
10/2019 - 05/2016
1Peritonitis
02/2021
1Cholangiocarcinoma
11/2018
1Seminoma
11/2017
1Chronic Pancreatitis
05/2016
1Mesothelioma
05/2016
1Adenocarcinoma of Lung
05/2016
1Ovarian Neoplasms (Ovarian Cancer)
05/2016
1Carcinoma (Carcinomatosis)
05/2016
1Bile Duct Neoplasms (Bile Duct Cancer)
05/2016
1Adenocarcinoma
09/2014
1Hepatocellular Carcinoma (Hepatoma)
05/2011

Drug/Important Bio-Agent (IBA)

5MesothelinIBA
10/2021 - 05/2016
3amatuximabIBA
10/2021 - 09/2018
3GemcitabineFDA Link
10/2021 - 09/2018
2Monoclonal AntibodiesIBA
10/2021 - 09/2018
2Glycoproteins (Glycoprotein)IBA
10/2021 - 02/2021
2LuciferasesIBA
10/2021 - 09/2018
1Immunoglobulin G (IgG)IBA
10/2021
1RamucirumabIBA
10/2019
1Paclitaxel (Taxol)FDA LinkGeneric
10/2019
1AC133 AntigenIBA
11/2018
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
09/2018
1Bleomycin (Blenoxane)FDA LinkGeneric
11/2017
1Etoposide (VP 16)FDA LinkGeneric
11/2017
1Cisplatin (Platino)FDA LinkGeneric
11/2017

Therapy/Procedure

4Therapeutics
10/2021 - 05/2016
2Neoadjuvant Therapy
10/2019 - 09/2014
2Drug Therapy (Chemotherapy)
11/2017 - 05/2011
1Adjuvant Chemotherapy
10/2021
1Immunotherapy
10/2017